Assessment of anticancer activity of Pulicaria undulata on hepatocellular carcinoma HepG2 cell line
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چکیده
منابع مشابه
ANTICANCER ACTIVITY OF Artemisia vulgaris ON HEPATOCELLULAR CARCINOMA (HEPG2) CELLS
Hepatocellular carcinoma is the fifth leading cancer causing death worldwide. Currently research focuses on the use of medicinal plants for the treatment of cancer, due to its resistance to chemotherapeutic agents. Objective: The present study pertains to the use of Artemisia vulgaris as a source of anticancer agent. The methanolic extract of the leaves were tested in vitro against HepG2 (hepat...
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Black seed (Nigella sativa) is considered as a biological response modifier. Thymoquinone (TQ) is the bioactive and the most abundant constituent of the volatile oil of this seed which has been shown to possess anti-inflammatory, antioxidant and anti-neoplastic effects. In this study, the effect of TQ on HepG2 cell line was investigated in an attempt to identify its potential mechanism of actio...
متن کاملIn Vitro Challenge using Thymoquinone on Hepatocellular Carcinoma (HepG2) Cell Line
Black seed (Nigella sativa) is considered as a biological response modifier. Thymoquinone (TQ) is the bioactive and the most abundant constituent of the volatile oil of this seed which has been shown to possess anti-inflammatory, antioxidant and anti-neoplastic effects. In this study, the effect of TQ on HepG2 cell line was investigated in an attempt to identify its potential mechanism of actio...
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Background and aim: Aberrant activation of diverse intracellular signaling pathways involved in differentiation, cell growth, apoptosis. These pathways include known oncogenic pathways such as Janus kinase-signal transducer and activator of transcription (JAK/STAT) pathway. The JAK/STAT signaling pathway plays an important role in many cellular functions. This pathway can be activated by variou...
متن کاملAntioxidant and Pro-oxidant Effects of Aminoguanidine on HepG-2 Hepatocellular Carcinoma Cell Line
Background and purpose: Hepatocellular carcinoma (HCC) is one of the most fatal cancers, so, proposing new anticancer agents is highly valuable. Production of reactive oxygen species (ROS) is increased in majority of cancers. Increase in ROS leads to cell damage and death. Aminoguanidine (AG) (pimagedine) is one of the compounds that can produce ROS at high concentrations. The present study was...
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ژورنال
عنوان ژورنال: Tumor Biology
سال: 2019
ISSN: 1010-4283,1423-0380
DOI: 10.1177/1010428319880080